Osama Mohamad, MD, PhD - 1/29/2020

Tags: prostate cancer, prostate cancer treatment, brachytherapy, high dose radiation, low dose radiation

Dr. Osama Mohamad, assistant professor, received his undergraduate degree at the American University of Beirut, in Beirut, Lebanon in 2006 with the highest honors. He then enrolled in the medical scientist training program (MSTP) at Emory University in Atlanta, and successfully finished his MD Ph.D. (Ph.D. in stem cells and regenerative medicine) in 2014. During his Ph.D., he received a Howard Hughes Medical Institute Fellowship award and completed a certificate program in clinical and translational research. He completed a transitional year internship at the University of Hawaii (where he received the resident of the year award), then finished residency training in radiation oncology at the University of Texas Southwestern (UTSW) Medical Center, in Dallas (where he was a chief resident). During residency, he spent a year pursuing a research fellowship at the National Institute of Radiological Sciences in Japan studying carbon ion radiotherapy for prostate cancer. Over his years in training, he received many awards including the resident of the year award and the RSNA Roentgen research award during his chief resident year at UTSW. He presented his research at multiple national and international meetings and published over 45 publications including a first author original research paper in Lancet Oncology.

Dr. Mohamad’s number one priority is his patients. He is interested in healthcare innovation with a focus on oncology. He is passionate about clinical care and bringing cutting-edge research and innovation to his patients. At UCSF, he will be treating genitourinary cancers with a special focus on prostate and kidney cancers using intensity-modulated radiotherapy (IMRT), stereotactic radiotherapy (SBRT), and HDR brachytherapy. He will build on the strong interdisciplinary cancer clinical programs in the departments of urology, radiation oncology, and medical oncology at UCSF to develop clinical research, clinical trials, and translational research in prostate and kidney cancers.
Interests:
Oncology, prostate cancer, kidney cancer, health innovation, healthcare entrepreneurship
  • Academic Collaboration
  • Academic Senate Committee Service
  • Multicenter Clinical Research
  • Community and Stakeholder Organizations
  • Companies and Entrepreneurs
  • Press
  • Prospective Donors

Education and Training:

American University of Beirut, Beirut B.S. 06/2006 Biology
Emory University, Atlanta MD 05/2014 Medicine
Emory University , Atlanta PhD 06/2014 Neuroscience and regenerative medicine
University of Texas Southwestern, Dallas 06/2019 Radiation Oncology Residency
National Institute of Radiological Sciences, Chiba, Japan 04/2018 Research fellowship in carbon ion radiotherapy

Awards and Honors:

University of Texas Southwestern Medical Center 2018  - 2019 Resident of the year chief resident award
University of Texas Southwestern Medical Center 2015  - 2019 RSNA Roentgen research award
Association of Residents in Radiation Oncology 2017  - 2018 ASTRO/ARRO Global Health Scholar Program Award
University of Hawaii Transitional Year Program 2014  - 2015 Resident of the year awad
Emory University 2008  - 2009 Crawford Long Anesthesiology Research Award
Alpha Omega Alpha Honors Medical Society 2006  - 2007 Carolyn Kuckein Student Research Award
American University of Beirut 2004  - 2005 Nicholas Jabr Award for Academic Excellence

Featured Publications:

  • Mohamad O, Tabuchi T, Nitta Y, Nomoto A, Sato A, Kasuya G, Makishima H, Choy H, Yamada S, Morishima T, Tsuji H, Miyashiro I, Kamada T; Risk of subsequent primary cancers after carbon ion radiotherapy, photon radiotherapy, or surgery for localised prostate cancer: a propensity score-weighted, retrospective, cohort study.; The Lancet. Oncology; 2019
  • Mohamad O, Tabuchi T, Morishima T, Makishima H, Miyashiro I, Tsuji H; Key considerations when reviewing subsequent primary cancers following radiotherapy - Authors' reply.; The Lancet. Oncology; 2019
  • View in: PubMed

In the News:

Carbon Ion Radiotherapy Lowers Risk for Later Primary Cancers in Prostate Cancer
Carbon-Ion RT May Cut Risk for Subsequent Tumors in Prostate Ca
Risk of Subsequent Primary Cancers After Carbon Ion Radiotherapy for Localized Prostate Cancer
Carbon ion radiotherapy may reduce future tumor risk after prostate cancer
Prostate Cancer: Carbon Ion Radiotherapy Reduces Future Risk
Carbon ion radiotherapy may reduce future tumor risk after prostate cancer

Publications:

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
List All   |   Timeline
  1. Lin MH, Yang M, Dougherty J, Tasson A, Zhang Y, Mohamad O, Dan T, Yan Y, Gu X, Timmerman R, Laack N, Beltran C. Radiation Therapy for Pediatric Brain Tumors using Robotic Radiation Delivery System and Intensity Modulated Proton Therapy. Pract Radiat Oncol. 2019 Sep 19. PMID: 31542454.
    View in: PubMed 
  2. Zhang Y, Schoenhals J, Christie A, Mohamad O, Wang C, Bowman I, Singla N, Hammers H, Courtney K, Bagrodia A, Margulis V, Desai N, Garant A, Choy H, Timmerman R, Brugarolas J, Hannan R. Stereotactic Ablative Radiation Therapy (SAbR) Used to Defer Systemic Therapy in Oligometastatic Renal Cell Cancer. Int J Radiat Oncol Biol Phys. 2019 Oct 01; 105(2):367-375. PMID: 31377159.
    View in: PubMed Article has an altmetric score of 1
  3. Rahimi A, Mohamad O, Albuquerque K, Kim DWN, Chen D, Thomas K, Wooldridge R, Rivers A, Leitch M, Rao R, Haley B, Ahn C, Garwood D, Spangler A. Novel hyaluronan formulation for preventing acute skin reactions in breast during radiotherapy: a randomized clinical trial. Support Care Cancer. 2019 Jul 04. PMID: 31273506.
    View in: PubMed 
  4. Mohamad O, Tabuchi T, Morishima T, Makishima H, Miyashiro I, Tsuji H. Key considerations when reviewing subsequent primary cancers following radiotherapy - Authors' reply. Lancet Oncol. 2019 Jun; 20(6):e292. PMID: 31162099.
    View in: PubMed 
  5. Fadel HA, El Ahmadieh TY, Plitt AR, Neeley OJ, Johnson Z, Aoun SG, Mohamad O, Timmerman R, Weprin BE. Oculomotor Schwannomas: A Systematic Review and Report of Two Pediatric Cases Treated with Fractionated Cyberknife Stereotactic Radiotherapy. World Neurosurg. 2019 Sep; 129:487-496. PMID: 31125775.
    View in: PubMed Article has an altmetric score of 3
  6. Doke K, Mohamad O, Royce TJ, Meyer J, Chen AM. Fellowship Training Programs in Radiation Oncology: A Snapshot From 2005 to 2017. Int J Radiat Oncol Biol Phys. 2019 07 15; 104(4):765-772. PMID: 30885774.
    View in: PubMed Article has an altmetric score of 11
  7. Mohamad O, Tabuchi T, Nitta Y, Nomoto A, Sato A, Kasuya G, Makishima H, Choy H, Yamada S, Morishima T, Tsuji H, Miyashiro I, Kamada T. Risk of subsequent primary cancers after carbon ion radiotherapy, photon radiotherapy, or surgery for localised prostate cancer: a propensity score-weighted, retrospective, cohort study. Lancet Oncol. 2019 May; 20(5):674-685. PMID: 30885458.
    View in: PubMed Article has an altmetric score of 729
  8. Makishima H, Yasuda S, Isozaki Y, Kasuya G, Okada N, Miyazaki M, Mohamad O, Matsufuji N, Yamada S, Tsuji H, Kamada T. Single fraction carbon ion radiotherapy for colorectal cancer liver metastasis: A dose escalation study. Cancer Sci. 2019 Jan; 110(1):303-309. PMID: 30417485.
    View in: PubMed Article has an altmetric score of 11
  9. Mkanna A, Mohamad O, Ramia P, Thebian R, Makki M, Tamim H, Jalbout W, Youssef B, Eid T, Geara F, Shahine B, Zeidan YH. Predictors of Cardiac Sparing in Deep Inspiration Breath-Hold for Patients With Left Sided Breast Cancer. Front Oncol. 2018; 8:564. PMID: 30538954.
    View in: PubMed 
  10. Mohamad O, Yamada S, Durante M. Clinical Indications for Carbon Ion Radiotherapy. Clin Oncol (R Coll Radiol). 2018 05; 30(5):317-329. PMID: 29402598.
    View in: PubMed Article has an altmetric score of 76
  11. Mohamad O, Imai R, Kamada T, Nitta Y, Araki N. Carbon ion radiotherapy for inoperable pediatric osteosarcoma. Oncotarget. 2018 May 01; 9(33):22976-22985. PMID: 29796166.
    View in: PubMed 5
  12. Mohamad O, Doke K, Marcrom S, Chen AM, Royce TJ, Meyer JJ. A Fellow's Fate: Employment Outcomes of Radiation Oncology Fellowship Graduates. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):16-17. PMID: 30102192.
    View in: PubMed Article has an altmetric score of 22
  13. Mohamad O, Diaz de Leon A, Schroeder S, Leiker A, Christie A, Zhang-Velten E, Trivedi L, Khan S, Desai NB, Laine A, Albuquerque K, Iyengar P, Arriaga Y, Courtney K, Gerber DE, Hammers H, Choy H, Timmerman R, Brugarolas J, Hannan R. Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy. Oncoimmunology. 2018; 7(7):e1440168. PMID: 29900043.
    View in: PubMed Article has an altmetric score of 28
  14. Mohamad O, Makishima H, Kamada T. Evolution of Carbon Ion Radiotherapy at the National Institute of Radiological Sciences in Japan. Cancers (Basel). 2018 Mar 06; 10(3). PMID: 29509684.
    View in: PubMed Article has an altmetric score of 119
  15. Mohamad O, Meyer JJ. Recent Trends in Radiation Oncology Fellowship Training in the United States. Int J Radiat Oncol Biol Phys. 2017 11 01; 99(3):539-540. PMID: 29280447.
    View in: PubMed Article has an altmetric score of 15
  16. Mohamad O, Sishc BJ, Saha J, Pompos A, Rahimi A, Story MD, Davis AJ, Kim DWN. Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research, with an Emphasis on DNA Damage/Repair. Cancers (Basel). 2017 Jun 09; 9(6). PMID: 28598362.
    View in: PubMed Article has an altmetric score of 330
  17. Mohamad O, Shiao J, Zhao B, Roach K, Ramirez E, Vo DT, Thomas K, Gu X, Spangler A, Albuquerque K, Rahimi A. Deep inspiration breathhold for left-sided breast cancer patients with unfavorable cardiac anatomy requiring internal mammary nodal irradiation. Pract Radiat Oncol. 2017 Nov - Dec; 7(6):e361-e367. PMID: 28666899.
    View in: PubMed Article has an altmetric score of 17
  18. Wei L, Wei ZZ, Jiang MQ, Mohamad O, Yu SP. Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke. Prog Neurobiol. 2017 Oct; 157:49-78. PMID: 28322920.
    View in: PubMed Article has an altmetric score of 936
  19. Song M, Yu SP, Mohamad O, Cao W, Wei ZZ, Gu X, Jiang MQ, Wei L. Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice. Neurobiol Dis. 2017 Feb; 98:9-24. PMID: 27884724.
    View in: PubMed 23
  20. Benyamini P, Lopez S, Cooper M, Mohamad O, Maldini G. Congenital Mesenteric Defect: An Uncommon Cause of Bowel Obstruction. Hawaii J Med Public Health. 2016 Feb; 75(2):46-7. PMID: 26918208.
    View in: PubMed 1
  21. Mohamad O, McFarlane M, Rahimi A. Absence of physiologic breast response to pregnancy and lactation after radiation therapy. Pract Radiat Oncol. 2016 Mar-Apr; 6(2):e25-6. PMID: 26553113.
    View in: PubMed 
  22. Chen D, Song M, Mohamad O, Yu SP. Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells. BMC Cancer. 2014 Sep 26; 14:716. PMID: 25255962.
    View in: PubMed Article has an altmetric score of 1141
  23. Mohamad O, Yu SP, Chen D, Ogle M, Song M, Wei L. Efficient neuronal differentiation of mouse ES and iPS cells using a rotary cell culture protocol. Differentiation. 2013 Nov-Dec; 86(4-5):149-58. PMID: 24480155.
    View in: PubMed 10
  24. Drury-Stewart D, Song M, Mohamad O, Guo Y, Gu X, Chen D, Wei L. Highly efficient differentiation of neural precursors from human embryonic stem cells and benefits of transplantation after ischemic stroke in mice. Stem Cell Res Ther. 2013 Aug 08; 4(4):93. PMID: 23928330.
    View in: PubMed Article has an altmetric score of 727
  25. Wei S, Sun J, Li J, Wang L, Hall CL, Dix TA, Mohamad O, Wei L, Yu SP. Acute and delayed protective effects of pharmacologically induced hypothermia in an intracerebral hemorrhage stroke model of mice. Neuroscience. 2013 Nov 12; 252:489-500. PMID: 23912033.
    View in: PubMed Article has an altmetric score of 135
  26. Mohamad O, Drury-Stewart D, Song M, Faulkner B, Chen D, Yu SP, Wei L. Vector-free and transgene-free human iPS cells differentiate into functional neurons and enhance functional recovery after ischemic stroke in mice. PLoS One. 2013; 8(5):e64160. PMID: 23717557.
    View in: PubMed 51
  27. Song M, Mohamad O, Chen D, Yu SP. Coordinated development of voltage-gated Na+ and K+ currents regulates functional maturation of forebrain neurons derived from human induced pluripotent stem cells. Stem Cells Dev. 2013 May 15; 22(10):1551-63. PMID: 23259973.
    View in: PubMed 23
  28. Majumder A, Banerjee S, Harrill JA, Machacek DW, Mohamad O, Bacanamwo M, Mundy WR, Wei L, Dhara SK, Stice SL. Neurotrophic effects of leukemia inhibitory factor on neural cells derived from human embryonic stem cells. Stem Cells. 2012 Nov; 30(11):2387-99. PMID: 22899336.
    View in: PubMed 32
  29. Song M, Mohamad O, Gu X, Wei L, Yu SP. Restoration of intracortical and thalamocortical circuits after transplantation of bone marrow mesenchymal stem cells into the ischemic brain of mice. Cell Transplant. 2013; 22(11):2001-15. PMID: 23069268.
    View in: PubMed Article has an altmetric score of 150
  30. Mohamad O, Song M, Wei L, Yu SP. Regulatory roles of the NMDA receptor GluN3A subunit in locomotion, pain perception and cognitive functions in adult mice. J Physiol. 2013 Jan 01; 591(1):149-68. PMID: 23006484.
    View in: PubMed Article has an altmetric score of 322
  31. Choi KE, Hall CL, Sun JM, Wei L, Mohamad O, Dix TA, Yu SP. A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice. FASEB J. 2012 Jul; 26(7):2799-810. PMID: 22459147.
    View in: PubMed 64
  32. Li J, Yu S, Lu Z, Mohamad O, Wei L. N-methyl-D-aspartate receptor subtype 3A promotes apoptosis in developing mouse brain exposed to hyperoxia. Neural Regen Res. 2012 Feb 05; 7(4):273-7. PMID: 25806068.
    View in: PubMed 
  33. Mohamad O, Chen D, Zhang L, Hofmann C, Wei L, Yu SP. Erythropoietin reduces neuronal cell death and hyperalgesia induced by peripheral inflammatory pain in neonatal rats. Mol Pain. 2011 Jul 21; 7:51. PMID: 21777449.
    View in: PubMed 12
  34. Drury-Stewart D, Song M, Mohamad O, Yu SP, Wei L. Small molecule promoted feeder free and adherent differentiation of functional neurons from human embryonic and induced pluripotent stem cells. J Stem Cells. 2011; 6(1):1-7. PMID: 22997841.
    View in: PubMed 9
  35. Li Y, Yu SP, Mohamad O, Genetta T, Wei L. Sublethal transient global ischemia stimulates migration of neuroblasts and neurogenesis in mice. Transl Stroke Res. 2010 Sep; 1(3):184-96. PMID: 21792374.
    View in: PubMed Article has an altmetric score of 131

Presentation

Link to Power Point Presentation